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KAHWEOL

Product Name
KAHWEOL
CAS No.
6894-43-5
Chemical Name
KAHWEOL
Synonyms
KAHWEOL;KAHWEOL USP/EP/BP;Kahweol DISCONTINUED, unstable;(3bS)-3b,4,5,6,7,8,9,10,10aα,10b-Decahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol;5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-;[3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
CBNumber
CB6117982
Molecular Formula
C20H26O3
Formula Weight
314.42
MOL File
6894-43-5.mol
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KAHWEOL Property

Melting point:
88-90℃
Boiling point:
476.6±45.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
DMSO:18.17(Max Conc. mg/mL);57.77(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:5):0.02(Max Conc. mg/mL);0.06(Max Conc. mM)
pka
14.43±0.40(Predicted)
form 
White to off-white solid.
LogP
3.380 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14015
Product name
Kahweol
Purity
≥98%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
14015
Product name
Kahweol
Purity
≥98%
Packaging
10mg
Price
$135
Updated
2024/03/01
Cayman Chemical
Product number
14015
Product name
Kahweol
Purity
≥98%
Packaging
25mg
Price
$315
Updated
2024/03/01
Biorbyt Ltd
Product number
orb594400
Product name
Kahweol
Packaging
20mg
Price
$391
Updated
2021/12/16
ChemScene
Product number
CS-0032794
Product name
Kahweol
Purity
≥98.0%
Packaging
20mg
Price
$429
Updated
2021/12/16
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KAHWEOL Chemical Properties,Usage,Production

Uses

Kahweol is an antioxidant diterpene contained in unfiltered coffee. Kahweol behaves as an anti-inflammatory and anti-angiogenic compound with potential use in antitumoral therapies. Recent research have demonstrated the ability of Kahweol in inhibiting metastasis by modulating expressions of MMPs and VEGF via STAT3 inactivation.

Definition

ChEBI: Kahweol is a diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties. It has a role as an angiogenesis inhibitor, an apoptosis inducer, an antioxidant, an anti-inflammatory agent, an antineoplastic agent and a plant metabolite. It is a diterpenoid, a member of furans, an organic heteropentacyclic compound, a tertiary alcohol and a primary alcohol.

KAHWEOL Preparation Products And Raw materials

Raw materials

Preparation Products

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KAHWEOL Suppliers

EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58

6894-43-5, KAHWEOLRelated Search:


  • 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-
  • KAHWEOL
  • (3bS)-3b,4,5,6,7,8,9,10,10aα,10b-Decahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
  • [3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
  • KAHWEOL USP/EP/BP
  • Kahweol DISCONTINUED, unstable
  • 6894-43-5
  • 6984-43-5
  • Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals